1H-benzo[d]imidazol-5-ol - Names and Identifiers
1H-benzo[d]imidazol-5-ol - Physico-chemical Properties
Molecular Formula | C7H6N2O
|
Molar Mass | 134.14 |
Density | 1.434±0.06 g/cm3(Predicted) |
Melting Point | 220-222℃ |
Boling Point | 469.1±18.0 °C(Predicted) |
Flash Point | 237.5°C |
Vapor Presure | 2.01E-09mmHg at 25°C |
pKa | 9.20±0.40(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.76 |
1H-benzo[d]imidazol-5-ol - Risk and Safety
Hazard Symbols | Xn - Harmful
|
Risk Codes | 22 - Harmful if swallowed
|
1H-benzo[d]imidazol-5-ol - Introduction
1H-benzimidazol-6-ol is an organic compound with the chemical formula C7H6N2O. Its nature is as follows:
1. Appearance: It is a colorless to light yellow solid.
2. melting point: its melting point is 139-143 degrees Celsius.
3. Solubility: It is soluble in organic solvents such as ethanol, chloroform and benzene.
The main uses of 1H-benzimidazol-6-ol include the following:
1. chemical reagent: it is often used as a reagent in chemical reactions.
2. Drug synthesis: It is used as an intermediate for the synthesis of certain drugs and plays an important role in the process of drug synthesis.
3. Biological activity research: It has a wide range of applications in biological activity research, such as drug screening and biological activity evaluation.
The preparation method of 1H-benzimidazol-6-ol can be carried out by the following steps:
1. Starting from aniline, a nucleophilic substitution reaction is first carried out using nitromethane to obtain a nitroso derivative of aniline.
2. continue to treat the nitroso derivative, add sulfuric acid to obtain nitroso ion, and dehydrate to generate benzimidazole.
3. Finally, the benzimidazole was oxidized under certain conditions to obtain 1H-benzimidazol-6-ol.
Note the following safety information when using and storing 1H-benzimidazol-6-ol:
1. 1H-benzimidazol-6-ol is an organic compound and should be operated in a well-ventilated environment.
2. Avoid contact with skin, eyes and respiratory tract. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
3. in storage, it should be kept in a cool, dry place, away from fire and combustible materials.
Last Update:2024-04-10 22:41:03